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Danielle M Townsley Selected Research

eltrombopag

1/2021Eltrombopag added to immunosuppression for children with treatment-naïve severe aplastic anaemia.
12/2020Eltrombopag monotherapy can improve hematopoiesis in patients with low to intermediate risk-1 myelodysplastic syndrome.
1/2020Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias.
1/2019Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ.
1/2019Eltrombopag promotes DNA repair in human hematopoietic stem and progenitor cells.
1/2019Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag.
1/2018Eltrombopag mobilizes iron in patients with aplastic anemia.
1/2017Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia.
12/2016Nontransplant therapy for bone marrow failure.
1/2015Eltrombopag in aplastic anemia.
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Danielle M Townsley Research Topics

Disease

15Aplastic Anemia (Anemia, Hypoplastic)
01/2021 - 07/2013
6Bone Marrow Failure Disorders
01/2019 - 07/2013
4Myelodysplastic Syndromes (Myelodysplastic Syndrome)
12/2020 - 01/2016
4Cytopenia
12/2020 - 01/2016
3Neoplasms (Cancer)
01/2022 - 01/2018
3Liver Diseases (Liver Disease)
01/2019 - 10/2014
2Fibrosis (Cirrhosis)
12/2020 - 01/2018
2Thrombocytopenia (Thrombopenia)
12/2020 - 07/2013
2Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
07/2013 - 07/2013
1Disease Progression
10/2020
1Genomic Instability
01/2019
1Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria)
07/2018
1Non-alcoholic Fatty Liver Disease
01/2018
1Alcoholic Fatty Liver
01/2018
1Hematologic Neoplasms (Hematological Malignancy)
01/2018
1Aneuploidy (Aneuploid)
12/2017
1Muscle Cramp (Cramp)
05/2016
1Immune System Diseases (Immune Disorders)
12/2015
1Dyskeratosis Congenita (X-Linked Dyskeratosis Congenita)
10/2014
1Pulmonary Fibrosis (Fibrosing Alveolitis)
10/2014
1Serum Sickness
09/2014
1Cytokine Release Syndrome
09/2014
1Chromosome Aberrations (Chromosome Abnormalities)
03/2014
1Sickle Cell Anemia (Hemoglobin S Disease)
07/2013
1Thrombotic Thrombocytopenic Purpura
07/2013
1Hemorrhage
07/2013
1Hemolysis
07/2013
1Pre-Eclampsia (Preeclampsia)
07/2013
1HELLP Syndrome
07/2013
1Anemia
07/2013
1Iron Deficiencies
07/2013

Drug/Important Bio-Agent (IBA)

12eltrombopagFDA Link
01/2021 - 07/2013
4Thrombopoietin (c-mpl Ligand)IBA
12/2020 - 07/2013
3Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA
01/2021 - 09/2014
3Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2021 - 01/2015
3Telomerase (Telomerase Reverse Transcriptase)IBA
01/2019 - 10/2014
3MicroRNAs (MicroRNA)IBA
01/2018 - 12/2015
2Thrombopoietin ReceptorsIBA
12/2020 - 01/2017
2CytokinesIBA
01/2019 - 09/2014
2AntibodiesIBA
07/2018 - 09/2014
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2018 - 12/2016
2IronIBA
01/2018 - 07/2013
2Biomarkers (Surrogate Marker)IBA
01/2018 - 01/2017
2Danazol (Azol)FDA LinkGeneric
12/2016 - 05/2016
2EnzymesIBA
05/2016 - 07/2013
2Pharmaceutical PreparationsIBA
01/2015 - 03/2014
1durvalumabIBA
01/2022
1tremelimumabIBA
01/2022
1Reticulin (Reticular Fiber)IBA
12/2020
1Monoclonal AntibodiesIBA
10/2020
1Immune Checkpoint InhibitorsIBA
10/2020
1InterferonsIBA
01/2019
1aerolysinIBA
07/2018
1Proteins (Proteins, Gene)FDA Link
07/2018
1RNA (Ribonucleic Acid)IBA
12/2017
1Small Cytoplasmic RNAIBA
12/2017
1Methotrexate (Mexate)FDA LinkGeneric
01/2016
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2016
1telomerase RNA (bTR)IBA
10/2014
1Immunoglobulin M (IgM)IBA
09/2014
1thymoglobulinFDA Link
09/2014
1Inosine Triphosphate (ITP)IBA
07/2013
1thiamine triphosphorate (TTP)IBA
07/2013
1romiplostimFDA Link
07/2013

Therapy/Procedure

6Therapeutics
01/2022 - 12/2015
1Intravenous Infusions
10/2020
1Transplantation
01/2019
1Aftercare (After-Treatment)
01/2018
1Stem Cell Transplantation
01/2016
1Platelet Transfusion (Blood Platelet Transfusions)
07/2013